Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial.

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Title: Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial.
Authors: Deng L; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., Taelman S; BIOBIX, Department of Data Analysis and Mathematical Modelling, Ghent University, 9000, Ghent, Belgium.; KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, 9000, Ghent, Belgium.; BioLizard nv, 9000, Ghent, Belgium., Olm MR; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA., Toe LC; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium.; Institut de Recherche en Sciences de la Santé (IRSS), Unité Nutrition et Maladies Métaboliques, Bobo-Dioulasso, Burkina Faso., Balini E; BioLizard nv, 9000, Ghent, Belgium., Ouédraogo LO; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium.; Centre Muraz, Bobo-Dioulasso, Burkina Faso., Bastos-Moreira Y; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium.; Center of Excellence in Mycotoxicology and Public Health, MYTOXSOUTH® Coordination Unit, Faculty of Pharmaceutical Sciences, Ghent University, 9000, Ghent, Belgium., Argaw A; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., Tesfamariam K; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., Sonnenburg ED; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA., Hanley-Cook GT; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., Ouédraogo M; Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique (AFRICSanté), Bobo-Dioulasso, Burkina Faso., Ganaba R; Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique (AFRICSanté), Bobo-Dioulasso, Burkina Faso., Van Criekinge W; BIOBIX, Department of Data Analysis and Mathematical Modelling, Ghent University, 9000, Ghent, Belgium., Huybregts L; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium.; Nutrition, Diets, and Health Unit, International Food Policy Research Institute (IFPRI), Washington, DC, USA., Stock M; KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, 9000, Ghent, Belgium., Kolsteren P; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., Sonnenburg JL; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Center for Human Microbiome Studies, Stanford University School of Medicine, Stanford, CA, USA., Lachat C; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium. carl.lachat@ugent.be., Dailey-Chwalibóg T; Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium. Trenton@Dailey-Chwalibog.com.; Agence de Formation de Recherche et d'Expertise en Santé pour l'Afrique (AFRICSanté), Bobo-Dioulasso, Burkina Faso. Trenton@Dailey-Chwalibog.com.
Source: Nature communications [Nat Commun] 2025 Mar 18; Vol. 16 (1), pp. 2683. Date of Electronic Publication: 2025 Mar 18.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-025-57838-y