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CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system.

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Title: CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system.
Authors: Salman A; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. ahmed.salman@ndcn.ox.ac.uk., Song WK; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Gangnum Yonsei Eye Clinic, Seoul, Republic of South Korea., Storm T; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., McClements ME; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., MacLaren RE; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. maclaren@eye.ox.ac.uk.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. maclaren@eye.ox.ac.uk.
Source: Gene therapy [Gene Ther] 2025 Mar; Vol. 32 (2), pp. 132-141. Date of Electronic Publication: 2025 Mar 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Salman+A%22">Salman A</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. ahmed.salman@ndcn.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Song+WK%22">Song WK</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Gangnum Yonsei Eye Clinic, Seoul, Republic of South Korea.<br /><searchLink fieldCode="AU" term="%22Storm+T%22">Storm T</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McClements+ME%22">McClements ME</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22MacLaren+RE%22">MacLaren RE</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. maclaren@eye.ox.ac.uk.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. maclaren@eye.ox.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229421525%22">Gene therapy</searchLink> [Gene Ther] 2025 Mar; Vol. 32 (2), pp. 132-141. <i>Date of Electronic Publication: </i>2025 Mar 18.
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        Value: 10.1038/s41434-025-00522-z
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              Text: 2025 Mar
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