A Randomized Clinical Trial of Prolonged Exposure Therapy With and Without Topiramate for Comorbid PTSD and Alcohol Use Disorder.
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| Title: | A Randomized Clinical Trial of Prolonged Exposure Therapy With and Without Topiramate for Comorbid PTSD and Alcohol Use Disorder. |
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| Authors: | Norman SB; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Luciano MT; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Panza KE; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Davis BC; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Lyons M; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Martis B; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Matthews SC; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Angkaw AC; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Haller M; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Lacefield K; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Brody AL; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Schnurr PP; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Batki SL; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Simpson TL; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson)., Anthenelli RM; National Center for PTSD, Executive Division, White River Junction, VT (Norman, Schnurr); VA Center of Excellence for Stress and Mental Health, San Diego (Norman, Martis); University of California San Diego School of Medicine, La Jolla (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody, Anthenelli); VA San Diego Healthcare System, San Diego (Norman, Luciano, Panza, Lyons, Martis, Matthews, Angkaw, Haller, Lacefield, Brody); James A. Haley Veterans Hospital, Tampa, FL (Davis); Morsani College of Medicine, University of South Florida, Tampa (Davis); Geisel School of Medicine at Dartmouth College, Hanover, NH, (Schnurr); San Francisco Veterans Affairs Health Care System, San Francisco (Batki); Department of Psychiatry, University of California, San Francisco (Batki); Center of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Healthcare System, Seattle (Simpson); Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle (Simpson). |
| Source: | The American journal of psychiatry [Am J Psychiatry] 2025 May 01; Vol. 182 (5), pp. 452-462. Date of Electronic Publication: 2025 Mar 19. |
| Publication Type: | Clinical Trial, Phase II; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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