Inhibition of the NLRP3 inflammasome using MCC950 reduces vincristine-induced adverse effects in an acute lymphoblastic leukemia patient-derived xenograft model.
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| Title: | Inhibition of the NLRP3 inflammasome using MCC950 reduces vincristine-induced adverse effects in an acute lymphoblastic leukemia patient-derived xenograft model. |
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| Authors: | Starobova H; Institute for Molecular Bioscience, The University of Queensland St Lucia Queensland Australia., McCalmont H; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, UNSW Centre for Childhood Cancer Research, UNSW Sydney Sydney New South Wales Australia., Shatunova S; Mater Research Institute, The University of Queensland South Brisbane Queensland Australia., Tay N; Institute for Molecular Bioscience, The University of Queensland St Lucia Queensland Australia., Smith CM; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, UNSW Centre for Childhood Cancer Research, UNSW Sydney Sydney New South Wales Australia., Robertson A; Institute for Molecular Bioscience, The University of Queensland St Lucia Queensland Australia.; School of Chemistry and Molecular Biosciences The University of Queensland St Lucia Queensland Australia., Winkler I; Mater Research Institute, The University of Queensland South Brisbane Queensland Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, UNSW Centre for Childhood Cancer Research, UNSW Sydney Sydney New South Wales Australia., Vetter I; Institute for Molecular Bioscience, The University of Queensland St Lucia Queensland Australia.; School of Pharmacy and Pharmaceutical Sciences The University of Queensland Woolloongabba Queensland Australia. |
| Source: | HemaSphere [Hemasphere] 2025 Mar 18; Vol. 9 (3), pp. e70092. Date of Electronic Publication: 2025 Mar 18 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2572-9241 |
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| DOI: | 10.1002/hem3.70092 |
