Effectiveness and Safety of Second-line Tyrosine Kinase Inhibitors After Discontinuation of First-line Immune-oncology Combination Therapy Because of Adverse Events in the Patients With Metastatic Renal Cell Carcinoma.

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Title: Effectiveness and Safety of Second-line Tyrosine Kinase Inhibitors After Discontinuation of First-line Immune-oncology Combination Therapy Because of Adverse Events in the Patients With Metastatic Renal Cell Carcinoma.
Authors: Takahashi M; Department of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan. Electronic address: matakaha35@hotmail.com., Matsushita Y; Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Kojima T; Department of Urology, Aichi Cancer Center, Nagoya, Japan., Osawa T; Department of Renal and Genitourinary Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan., Sazuka T; Department of Urology, Graduate School of Medicine, Chiba University, Chiba, Japan., Hatakeyama S; Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Goto K; Department of Urology, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan., Numakura K; Department of Urology, Akita University Graduate School of Medicine, Akita, Japan., Yamana K; Department of Urology and Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Kandori S; Department of Urology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Fujita K; Department of Urology, Kindai University Faculty of Medicine, Osakasayama, Japan., Ueda K; Department of Urology, Kurume University School of Medicine, Kurume, Japan., Tanaka H; Department of Urology, Institute of Science Tokyo, Tokyo, Japan., Tomida R; Department of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan., Kurahashi T; Department of Urology, Hyogo Prefectural Cancer Center, Akashi, Japan., Bando Y; Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan., Kimura T; Department of Urology, The Jikei University School of Medicine, Tokyo, Japan., Nishiyama N; Department of Urology, Faculty of Medicine, University of Toyama, Toyama, Japan., Yamashita S; Department of Urology, Wakayama Medical University, Wakayama, Japan., Taniguchi H; Department of Urology and Andrology, Kansai Medical University, Hirakata, Japan., Monji K; Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Ishiyama R; Department of Urology, Tokyo Women's Medical University, Tokyo, Japan., Kawasaki Y; Department of Urology, Tohoku University Graduate School of Medicine, Sendai, Japan., Kato T; Department of Urology, Faculty of Medicine, Kagawa University, Kita-gun, Japan., Tatarano S; Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Masui K; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Nakamura E; Department of Urology, National Cancer Center Hospital, Tokyo, Japan., Kaneko T; Department of Urology, Teikyo University School of Medicine, Tokyo, Japan., Miyake M; Department of Urology, Nara Medical University, Nara, Japan., Kitano G; Department of Urology, Aichi Cancer Center, Nagoya, Japan., Motoshima T; Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Shiraishi Y; Department of Urology, Shizuoka General Hospital, Shizuoka, Japan., Kira S; Department of Urology, University of Yamanashi Graduate School of Medical Sciences, Chuo, Japan., Murashima T; Department of Urology, Faculty of Medicine, Miyazaki University Hospital, Miyazaki, Japan., Hara H; Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan., Matsumura M; Department of Urology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan., Kitamura H; Department of Urology, Faculty of Medicine, University of Toyama, Toyama, Japan., Miyake H; Division of Urology, Kobe University Graduate School of Medicine, Kobe, Japan., Furukawa J; Department of Urology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Corporate Authors: Japanese Urological Oncology Group
Source: Clinical genitourinary cancer [Clin Genitourin Cancer] 2025 Jun; Vol. 23 (3), pp. 102322. Date of Electronic Publication: 2025 Feb 26.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101260955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-0682 (Electronic) Linking ISSN: 15587673 NLM ISO Abbreviation: Clin Genitourin Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1938-0682
DOI:10.1016/j.clgc.2025.102322