Empirical pharmacodynamic model of phenylephrine and intrathecal bupivacaine for mean arterial pressure prediction in obstetric patients presenting for elective cesarean delivery under spinal anesthesia.

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Title: Empirical pharmacodynamic model of phenylephrine and intrathecal bupivacaine for mean arterial pressure prediction in obstetric patients presenting for elective cesarean delivery under spinal anesthesia.
Authors: Davoud SC; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, L1, Boston, MA, 02115, USA., Ozaslan B; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA.; Sansum Diabetes Research Institute, Santa Barbara, CA, USA., Aiello EM; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA.; Sansum Diabetes Research Institute, Santa Barbara, CA, USA., Kleinlein R; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, L1, Boston, MA, 02115, USA., Eberhard B; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, L1, Boston, MA, 02115, USA., Hassan H; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, L1, Boston, MA, 02115, USA.; University of New England College of Osteopathic Medicine, Biddeford, ME, USA., Doyle FJ 3rd; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Boston, MA, USA.; Sansum Diabetes Research Institute, Santa Barbara, CA, USA., Kovacheva VP; Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, L1, Boston, MA, 02115, USA. vkovacheva@bwh.harvard.edu.
Source: Journal of clinical monitoring and computing [J Clin Monit Comput] 2025 Aug; Vol. 39 (4), pp. 775-785. Date of Electronic Publication: 2025 Mar 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 9806357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2614 (Electronic) Linking ISSN: 13871307 NLM ISO Abbreviation: J Clin Monit Comput Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1573-2614
DOI:10.1007/s10877-025-01288-w