New pyrrolo[3,4-d] isoxazolidines hybrid with furan as antitumor agents and multi-target enzyme inhibitors: Synthesis and in silico study.
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| Title: | New pyrrolo[3,4-d] isoxazolidines hybrid with furan as antitumor agents and multi-target enzyme inhibitors: Synthesis and in silico study. |
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| Authors: | Said AI; Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt. Electronic address: awadsaid@aun.edu.eg., Ewes WA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt. Electronic address: wafaa_ewes@mans.edu.eg., Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt., El-Rashedy AA; Natural and Microbial Products Department, National Research Center (NRC), Egypt; Department Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia 32897, Egypt., Ahmed M; Chemistry Department, Faculty of Science, New Valley University, El-Kharja, 72511, Egypt. Electronic address: drmostafa@scinvu.au.edu.eg. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2025 Jun 01; Vol. 159, pp. 108377. Date of Electronic Publication: 2025 Mar 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1090-2120 |
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| DOI: | 10.1016/j.bioorg.2025.108377 |