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New pyrrolo[3,4-d] isoxazolidines hybrid with furan as antitumor agents and multi-target enzyme inhibitors: Synthesis and in silico study.

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Title: New pyrrolo[3,4-d] isoxazolidines hybrid with furan as antitumor agents and multi-target enzyme inhibitors: Synthesis and in silico study.
Authors: Said AI; Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt. Electronic address: awadsaid@aun.edu.eg., Ewes WA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt. Electronic address: wafaa_ewes@mans.edu.eg., Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt., El-Rashedy AA; Natural and Microbial Products Department, National Research Center (NRC), Egypt; Department Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia 32897, Egypt., Ahmed M; Chemistry Department, Faculty of Science, New Valley University, El-Kharja, 72511, Egypt. Electronic address: drmostafa@scinvu.au.edu.eg.
Source: Bioorganic chemistry [Bioorg Chem] 2025 Jun 01; Vol. 159, pp. 108377. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: New pyrrolo[3,4-d] isoxazolidines hybrid with furan as antitumor agents and multi-target enzyme inhibitors: Synthesis and in silico study.
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  Data: <searchLink fieldCode="AU" term="%22Said+AI%22">Said AI</searchLink>; Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt. Electronic address: awadsaid@aun.edu.eg.<br /><searchLink fieldCode="AU" term="%22Ewes+WA%22">Ewes WA</searchLink>; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt. Electronic address: wafaa_ewes@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Hamdi+A%22">Hamdi A</searchLink>; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura university, Mansoura 35516, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Rashedy+AA%22">El-Rashedy AA</searchLink>; Natural and Microbial Products Department, National Research Center (NRC), Egypt; Department Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia 32897, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+M%22">Ahmed M</searchLink>; Chemistry Department, Faculty of Science, New Valley University, El-Kharja, 72511, Egypt. Electronic address: drmostafa@scinvu.au.edu.eg.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2025 Jun 01; Vol. 159, pp. 108377. <i>Date of Electronic Publication: </i>2025 Mar 17.
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        Value: 10.1016/j.bioorg.2025.108377
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              Text: 2025 Jun 01
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