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Expanding the therapeutic role of highly purified cannabidiol in monogenic epilepsies: A multicenter real-world study.

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Title: Expanding the therapeutic role of highly purified cannabidiol in monogenic epilepsies: A multicenter real-world study.
Authors: Cerulli Irelli E; Department of Human Neurosciences, Sapienza University, Rome, Italy., Mazzeo A; Department of Human Neurosciences, Sapienza University, Rome, Italy., Caraballo RH; Department of Neurology, Hospital de Pediatría 'Prof. Dr. Juan P. Garrahan', Buenos Aires, Argentina., Perulli M; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Moloney PB; Department of Neurology, Mater Misericordiae University Hospital, Dublin, Ireland., Peña-Ceballos J; Department of Neurology, Beaumont Hospital, Dublin, Ireland., Rubino M; Department of Neuroscience, Reproductive Sciences, and Odontostomatology, Federico II University of Naples, Naples, Italy., Mieszczanek KM; Danish Epilepsy Center, Dianalund, Denmark., Santangelo A; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Licchetta L; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., De Giorgis V; Brain and Behavioral Sciences Department, University of Pavia, Pavia, Italy.; Department of Child Neurology and Psychiatry, Childhood and Adolescence Epilepsy Center, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Mondino Foundation, Pavia, Italy., Reyes Valenzuela G; Department of Neurology, Hospital de Pediatría 'Prof. Dr. Juan P. Garrahan', Buenos Aires, Argentina., Casellato S; Child Neuropsychiatry Unit, Department of Woman's and Child's Health, Center of Pediatric Epilepsies, Azienda Ospedaliera Universitaria, Sassari, University of Sassari, Sassari, Italy., Cesaroni E; Child Neurology and Psychiatric Unit, Pediatric Hospital G. Salesi, Azienda Ospedaliero-Universitaria Delle Marche, Ancona, Italy., Operto FF; Department of Science of Health, School of Medicine, University of Catanzaro, Catanzaro, Italy., Domínguez-Carral J; Epilepsy Unit, Department of Child Neurology, Institut de Recerca Sant Joan de Déu, Barcelona, Spain., Ramírez-Camacho A; Epilepsy Unit, Department of Child Neurology, Institut de Recerca Sant Joan de Déu, Barcelona, Spain., Ferretti A; Department of Neuroscience, Mental Health, and Sense Organs, Faculty of Medicine and Psychology, Sant'Andrea Hospital, Rome, Italy., Santangelo G; Child Neuropsychiatry Department, Itituto Mediterraneo di Eccellenza Pediatrica-Azienda di Rilievo Nazionale ad Alta Sspecializzazione, Civico, Palermo, Italy., Aledo-Serrano A; Epilepsy and Neurogenetics Unit, Vithas La Milagrosa University Hospital, Vithas Hospital Group, Madrid, Spain., Rüegger A; Department of Neuropediatrics, University Children's Hospital, Zurich, Switzerland., Mancardi MM; Child Neuropsychiatry Unit, member of the European Reference Network for Rare and Complex Epilepsies, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Prato G; Child Neuropsychiatry Unit, member of the European Reference Network for Rare and Complex Epilepsies, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Riva A; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Bergonzini L; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Cordelli DM; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Bonanni P; Epilepsy and Clinical Neurophysiology Unit, Scientific Institute for Research, Hospitalization and Healthcare, E. Medea, Conegliano, Italy., Bisulli F; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Di Gennaro G; Istituto di Ricovero e Cura a Carattere Scientifico 'Neuromed', Pozzilli, Italy., Matricardi S; Department of Pediatrics, University of Chieti-Pescara, Chieti, Italy., Striano P; Child Neuropsychiatry Unit, member of the European Reference Network for Rare and Complex Epilepsies, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Delanty N; Department of Neurology, Beaumont Hospital, Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; Research Ireland FutureNeuro Centre, Dublin, Ireland., Marini C; Child Neurology and Psychiatric Unit, Pediatric Hospital G. Salesi, Azienda Ospedaliero-Universitaria Delle Marche, Ancona, Italy., Battaglia D; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Di Bonaventura C; Department of Human Neurosciences, Sapienza University, Rome, Italy., Ramantani G; Department of Neuropediatrics, University Children's Hospital, Zurich, Switzerland., Gardella E; Danish Epilepsy Center, Dianalund, Denmark.; University of Southern Denmark, Odense, Denmark., Orsini A; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Coppola A; Department of Neuroscience, Reproductive Sciences, and Odontostomatology, Federico II University of Naples, Naples, Italy.
Corporate Authors: GENE‐CBD Study Group
Source: Epilepsia [Epilepsia] 2025 Jul; Vol. 66 (7), pp. 2253-2267. Date of Electronic Publication: 2025 Mar 24.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1528-1167
DOI:10.1111/epi.18378