Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.

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Bibliographic Details
Title: Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.
Authors: Chen KY; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. chenk@ifrec.osaka-u.ac.jp., Kibayashi T; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Giguelay A; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Hata M; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Nakajima S; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Mikami N; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Takeshima Y; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Ichiyama K; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Omiya R; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Ludwig LS; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Hattori K; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Sakaguchi S; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. shimon@ifrec.osaka-u.ac.jp.; Department of Experimental Pathology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan. shimon@ifrec.osaka-u.ac.jp.
Source: Nature [Nature] 2025 Jun; Vol. 642 (8066), pp. 191-200. Date of Electronic Publication: 2025 Mar 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-08795-5