View in EDS

Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.

Saved in:
Bibliographic Details
Title: Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.
Authors: Chen KY; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. chenk@ifrec.osaka-u.ac.jp., Kibayashi T; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Giguelay A; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Hata M; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Nakajima S; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Mikami N; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Takeshima Y; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Ichiyama K; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan., Omiya R; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Ludwig LS; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Hattori K; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan., Sakaguchi S; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. shimon@ifrec.osaka-u.ac.jp.; Department of Experimental Pathology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan. shimon@ifrec.osaka-u.ac.jp.
Source: Nature [Nature] 2025 Jun; Vol. 642 (8066), pp. 191-200. Date of Electronic Publication: 2025 Mar 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40140585
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Chen+KY%22">Chen KY</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. chenk@ifrec.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kibayashi+T%22">Kibayashi T</searchLink>; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Giguelay+A%22">Giguelay A</searchLink>; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hata+M%22">Hata M</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+S%22">Nakajima S</searchLink>; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Mikami+N%22">Mikami N</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Takeshima+Y%22">Takeshima Y</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ichiyama+K%22">Ichiyama K</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Omiya+R%22">Omiya R</searchLink>; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Ludwig+LS%22">Ludwig LS</searchLink>; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hattori+K%22">Hattori K</searchLink>; Joint Research Chair of Innovative Drug Discovery in Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Research Division, Chugai Pharmaceutical Co. Ltd, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Sakaguchi+S%22">Sakaguchi S</searchLink>; Laboratory of Experimental Immunology, Immunology Frontier Research Center, Osaka University, Osaka, Japan. shimon@ifrec.osaka-u.ac.jp.; Department of Experimental Pathology, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan. shimon@ifrec.osaka-u.ac.jp.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Jun; Vol. 642 (8066), pp. 191-200. <i>Date of Electronic Publication: </i>2025 Mar 26.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40140585
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41586-025-08795-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 191
    Titles:
      – TitleFull: Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chen KY
      – PersonEntity:
          Name:
            NameFull: Kibayashi T
      – PersonEntity:
          Name:
            NameFull: Giguelay A
      – PersonEntity:
          Name:
            NameFull: Hata M
      – PersonEntity:
          Name:
            NameFull: Nakajima S
      – PersonEntity:
          Name:
            NameFull: Mikami N
      – PersonEntity:
          Name:
            NameFull: Takeshima Y
      – PersonEntity:
          Name:
            NameFull: Ichiyama K
      – PersonEntity:
          Name:
            NameFull: Omiya R
      – PersonEntity:
          Name:
            NameFull: Ludwig LS
      – PersonEntity:
          Name:
            NameFull: Hattori K
      – PersonEntity:
          Name:
            NameFull: Sakaguchi S
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2025 Jun
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
          Numbering:
            – Type: volume
              Value: 642
            – Type: issue
              Value: 8066
          Titles:
            – TitleFull: Nature
              Type: main
ResultId 1