Exploring Si-phthalocyanines with different valency for PSMA-targeted photodynamic therapy: Synthesis and preclinical validation.

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Title: Exploring Si-phthalocyanines with different valency for PSMA-targeted photodynamic therapy: Synthesis and preclinical validation.
Authors: Dinatale V; Department of Molecular Biotechnology and Health Sciences, University of Turin, Piazza Nizza 44bis, Turin, Italy; Department of Radiology and Nuclear Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands., Capozza M; Department of Molecular Biotechnology and Health Sciences, University of Turin, Piazza Nizza 44bis, Turin, Italy., Stefania R; Department of Science and Technological Innovation, Università del Piemonte Orientale, Viale Teresa Michel 11, Alessandria, Italy., Liuzzi S; Department of Molecular Biotechnology and Health Sciences, University of Turin, Piazza Nizza 44bis, Turin, Italy., de Bruijn HS; Centre for Optical Diagnostics and Therapy, Department of Otorhinolaryngology and Head & Neck Surgery, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands., McMorrow R; Department of Radiology and Nuclear Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands., Zambito G; Department of Radiology and Nuclear Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands., Robinson D; Centre for Optical Diagnostics and Therapy, Department of Otorhinolaryngology and Head & Neck Surgery, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands., Mezzanotte L; Department of Radiology and Nuclear Medicine, Erasmus MC Cancer Institute, Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam, the Netherlands. Electronic address: l.mezzanotte@erasmusmc.nl., Terreno E; Department of Molecular Biotechnology and Health Sciences, University of Turin, Piazza Nizza 44bis, Turin, Italy. Electronic address: enzo.terreno@unito.it.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2025 Jun 05; Vol. 290, pp. 117562. Date of Electronic Publication: 2025 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1768-3254
DOI:10.1016/j.ejmech.2025.117562