Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial.

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Title: Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial.
Authors: Herrmann JJ; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Brunner-La Rocca HP; Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands.; Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands., Baltussen LEHJM; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Beckers-Wesche F; Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands., Bekkers SCAM; Department of Cardiology, Bernhoven Hospital, Uden, the Netherlands., Bellersen L; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., van Eck JWM; Department of Cardiology, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., Hassing HC; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Jaarsma T; Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Linssen GCM; Department of Cardiology, Hospital Group Twente, Almelo/Hengelo, the Netherlands., Pisters R; Department of Cardiology, Rijnstate Hospital, Arnhem, the Netherlands., Sanders-van Wijk S; Department of Cardiology, Zuyderland Medical Center, Heerlen/Sittard-Geleen, the Netherlands., Verdijk MHI; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands., Handoko ML; Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., van der Meer P; Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands., Verbrugge FH; Centre for Cardiovascular Diseases, University Hospital Brussels, Jette, Belgium.; Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium., Januzzi JL Jr; Baim Institute for Clinical Research, Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Bayés-Genís A; Cardiology Service, Hospital Universitari Germans Trias i Pujol, CIBERVC, Badalona, Spain., Nieuwlaat R; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Rodwell L; IQ Health Department, Radboud University Medical Center, Nijmegen, the Netherlands., Gommans DHF; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Cardiology, Máxima Medical Center, Veldhoven, the Netherlands., van Kimmenade RRJ; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands. rolandvank@hotmail.com.
Source: Nature medicine [Nat Med] 2025 Jun; Vol. 31 (6), pp. 2062-2068. Date of Electronic Publication: 2025 Mar 30.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-170X
DOI:10.1038/s41591-025-03628-4