Stability and DNA Methyltransferase Activity of DNMT3A are Maintained by Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation.

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Title: Stability and DNA Methyltransferase Activity of DNMT3A are Maintained by Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation.
Authors: Yonezawa T; Molecular and Cellular Biology Department; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX., Rutter JC; Department of Medical Oncology, Dana-Farber Cancer Institute, Division of Hematology, Brigham and Women's Hospital, and Broad Institute of MIT and Harvard, Cambridge, MA., Ramabadran R; Molecular and Cellular Biology Department; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX., Sundaramurthy V; Molecular and Cellular Biology Department; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX., Datar G; Molecular and Cellular Biology Department; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX., Slabicki M; Krantz Family Center for Cancer Research, Massachusetts General Hospital Cancer Center, Boston, MA., Goodell MA; Molecular and Cellular Biology Department; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jun 27. Date of Electronic Publication: 2025 Jun 27.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.03.05.641683