The impact of therapeutic radiation on drug distribution across the blood-brain barrier in normal mouse brain and orthotopic glioblastoma tumors.

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Title: The impact of therapeutic radiation on drug distribution across the blood-brain barrier in normal mouse brain and orthotopic glioblastoma tumors.
Authors: Zhang W; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Grams MP; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Oberoi RK; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Oh JH; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Decker PA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Sio TT; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Talele S; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Wilson ZC; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Connors MA; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Bakken KK; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Carlson BL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Ott LL; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Tryggestad EJ; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Eckel Passow JE; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA., Elmquist WF; Brain Barriers Research Center, Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Source: Neuro-oncology [Neuro Oncol] 2025 Oct 14; Vol. 27 (9), pp. 2250-2261.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1523-5866
DOI:10.1093/neuonc/noaf093