Advancing clinical response against glioblastoma: Evaluating SHP1705 CRY2 activator efficacy in preclinical models and safety in phase I trials.
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| Title: | Advancing clinical response against glioblastoma: Evaluating SHP1705 CRY2 activator efficacy in preclinical models and safety in phase I trials. |
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| Authors: | Chan P; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Nagai Y; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan., Wu Q; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Hovsepyan A; Small Animal Imaging Core, Department of Radiology, Children's Hospital Los Angeles, California, USA., Mkhitaryan S; Small Animal Imaging Core, Department of Radiology, Children's Hospital Los Angeles, California, USA., Wang J; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Karapetyan G; Small Animal Imaging Core, Department of Radiology, Children's Hospital Los Angeles, California, USA., Kamenecka T; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida, USA., Solt LA; The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida, USA., Cope J; Synchronicity Pharma, San Jose, California, USA., Moats RA; Small Animal Imaging Core, Department of Radiology, Children's Hospital Los Angeles, California, USA., Hirota T; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan., Rich JN; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Kay SA; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. |
| Source: | Neuro-oncology [Neuro Oncol] 2025 Sep 08; Vol. 27 (7), pp. 1772-1786. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1523-5866 |
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| DOI: | 10.1093/neuonc/noaf089 |
