Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus.

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Title: Requirements and Study Design for the Next Proton FLASH Clinical Trials: an International Multidisciplinary Delphi Consensus.
Authors: Klaver YLB; HollandPTC, Delft, The Netherlands; Department of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: y.klaver@hollandptc.nl., Hoogeman MS; HollandPTC, Delft, The Netherlands; Department of Radiotherapy, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Lu QR; Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Bradley JD; Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania., Choi JI; Department of Radiation Oncology, New York Proton Center, New York, New York; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York., Ferris MJ; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland; Maryland Proton Treatment Center, Baltimore, Maryland., Grau C; Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark., Guha C; Department of Radiation Oncology, Montefiore University Hospital, Bronx, New York., Lin H; Department of Radiation Oncology, New York Proton Center, New York, New York; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Radiation Oncology, Montefiore University Hospital, Bronx, New York., Lin L; Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia., Mascia AE; Cincinnati Children's Hospital Medical Center, Cancer and Blood Disease Institute, Division of Oncology, Cincinnati, Ohio., Moerman AM; HollandPTC, Delft, The Netherlands., Poulsen PR; Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Shi LZ; Departments of Microbiology, Pharmacology & Toxicology; The Immunology Institute; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama., Singers Sørensen B; Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Experimental Clinical Oncology, Aarhus University, Denmark., Tian S; Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia., Vozenin MC; Radiotherapy and Radiobiology Sector, Radiation Therapy Service, University Hospital of Geneva, Geneva, Switzerland., Willey CD; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama., Zhou S; Radiation Oncology Department, University of Nebraska Medical Center, Omaha, Nebraska., Amos RA; Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom., Hawkins M; Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom; Clinical Oncology, University College London Hospitals NHS Foundation Trust, London, United Kingdom., Simone CB 2nd; Department of Radiation Oncology, New York Proton Center, New York, New York; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Source: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2025 Sep 01; Vol. 123 (1), pp. 296-305. Date of Electronic Publication: 2025 Mar 31.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-355X
DOI:10.1016/j.ijrobp.2025.03.047