Transcript-targeted antigen mapping reveals the potential of POSTN splicing junction epitopes in glioblastoma immunotherapy.

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Title: Transcript-targeted antigen mapping reveals the potential of POSTN splicing junction epitopes in glioblastoma immunotherapy.
Authors: Xiong Z; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.; Xiangya School of Medicine, Central South University, Changsha, Hunan, China., Sneiderman CT; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Kuminkoski CR; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Reinheimer J; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Schwegman L; Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA., Sever RE; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Habib A; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Hu B; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Agnihotri S; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Rajasundaram D; Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Zinn PO; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Forsthuber TG; Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA., Pollack IF; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Li X; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Hunan International Scientific and Technological Cooperation Base of Brain Tumor Research, Xiangya Hospital, Central South University, Changsha, Hunan, China., Raphael I; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA., Kohanbash G; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu.; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu.
Source: Genes and immunity [Genes Immun] 2025 Jun; Vol. 26 (3), pp. 190-199. Date of Electronic Publication: 2025 Apr 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5470
DOI:10.1038/s41435-025-00326-6