Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells.

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Title: Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cells.
Authors: Rose I; Institute of Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, SW17 0RE, UK., Greenwood M; Department of Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK., Biggart M; Division of Genetic, Environmental and Inhalational Disease, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Baumlin N; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Tarran R; Division of Genetic, Environmental and Inhalational Disease, University of Kansas Medical Center, Kansas City, KS, 66160, USA., Hart SL; Department of Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, WC1N 1EH, UK., Baines DL; Institute of Infection and Immunity, School of Health and Medical Sciences, City St George's, University of London, London, SW17 0RE, UK. d.baines@sgul.ac.uk.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Apr 07; Vol. 82 (1), pp. 144. Date of Electronic Publication: 2025 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1420-9071
DOI:10.1007/s00018-025-05587-y