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Large-scale discovery, analysis, and design of protein energy landscapes.

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Title: Large-scale discovery, analysis, and design of protein energy landscapes.
Authors: Ferrari ÁJR; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Dixit SM; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Thibeault J; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Garcia M; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Houliston S; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada., Ludwig RW; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Notin P; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Phoumyvong CM; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Martell CM; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Jung MD; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Tsuboyama K; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Current address: Institute of Industrial Science, The University of Tokyo, Tokyo, Japan., Carter L; Department of Biochemistry, University of Washington, Seattle, WA, USA. Current address: Bill & Melinda Gates Medical Research Institute., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada., Guttman M; Department of Medicinal Chemistry, University of Washington, Seattle, WA, USA., Rocklin GJ; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 25. Date of Electronic Publication: 2025 Mar 25.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ferrari+ÁJR%22">Ferrari ÁJR</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Dixit+SM%22">Dixit SM</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Thibeault+J%22">Thibeault J</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+M%22">Garcia M</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Houliston+S%22">Houliston S</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada.<br /><searchLink fieldCode="AU" term="%22Ludwig+RW%22">Ludwig RW</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Notin+P%22">Notin P</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Phoumyvong+CM%22">Phoumyvong CM</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Martell+CM%22">Martell CM</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Jung+MD%22">Jung MD</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Tsuboyama+K%22">Tsuboyama K</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Current address: Institute of Industrial Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Carter+L%22">Carter L</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA, USA. Current address: Bill & Melinda Gates Medical Research Institute.<br /><searchLink fieldCode="AU" term="%22Arrowsmith+CH%22">Arrowsmith CH</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5G 2M9, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada.<br /><searchLink fieldCode="AU" term="%22Guttman+M%22">Guttman M</searchLink>; Department of Medicinal Chemistry, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rocklin+GJ%22">Rocklin GJ</searchLink>; Department of Pharmacology & Center for Synthetic Biology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
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