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A minimal CRISPR polymerase produces decoy cyclic nucleotides to detect phage anti-defense proteins.

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Title: A minimal CRISPR polymerase produces decoy cyclic nucleotides to detect phage anti-defense proteins.
Authors: Sullivan AE; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Nabhani A; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA., Schinkel K; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Dinh DM; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA., Duncan ML; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Ednacot EMQ; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA., Hoffman CRK; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Izrailevsky DS; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA., Kibby EM; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Nagy TA; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Nguyen CM; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, University of California Irvine, Irvine, CA, USA., Tak U; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Burroughs AM; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Aravind L; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA., Whiteley AT; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA., Morehouse BR; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA.; Institute for Immunology, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 30. Date of Electronic Publication: 2025 Mar 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A minimal CRISPR polymerase produces decoy cyclic nucleotides to detect phage anti-defense proteins.
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  Data: <searchLink fieldCode="AU" term="%22Sullivan+AE%22">Sullivan AE</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Nabhani+A%22">Nabhani A</searchLink>; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schinkel+K%22">Schinkel K</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Dinh+DM%22">Dinh DM</searchLink>; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Duncan+ML%22">Duncan ML</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Ednacot+EMQ%22">Ednacot EMQ</searchLink>; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hoffman+CRK%22">Hoffman CRK</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Izrailevsky+DS%22">Izrailevsky DS</searchLink>; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kibby+EM%22">Kibby EM</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Nagy+TA%22">Nagy TA</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+CM%22">Nguyen CM</searchLink>; Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, University of California Irvine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tak+U%22">Tak U</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Burroughs+AM%22">Burroughs AM</searchLink>; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Aravind+L%22">Aravind L</searchLink>; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Whiteley+AT%22">Whiteley AT</searchLink>; Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.<br /><searchLink fieldCode="AU" term="%22Morehouse+BR%22">Morehouse BR</searchLink>; Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, USA.; Department of Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA.; Institute for Immunology, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.
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