Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins.
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| Title: | Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins. |
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| Authors: | Gong JN; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia. gongjianan@cnilas.org.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. gongjianan@cnilas.org.; NHC Key Laboratory of Human Disease Comparative Medicine, The Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model, Beijing, China. gongjianan@cnilas.org., Djajawi TM; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia., Moujalled DM; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Australian Centre for Blood Diseases, Alfred Health-Monash University, Melbourne, VIC, Australia., Pomilio G; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Australian Centre for Blood Diseases, Alfred Health-Monash University, Melbourne, VIC, Australia., Khong T; Australian Centre for Blood Diseases, Alfred Health-Monash University, Melbourne, VIC, Australia.; Department of Clinical Haematology, The Alfred Hospital, Melbourne, VIC, Australia.; Malignant Haematology and Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia., Zhang LP; NHC Key Laboratory of Human Disease Comparative Medicine, The Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model, Beijing, China., Fedele PL; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Department of Haematology, Monash Health, Clayton, VIC, Australia.; School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Low MS; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Department of Haematology, Monash Health, Clayton, VIC, Australia.; School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Anderson MA; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Riffkin CD; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia., White CA; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; oNKo-Innate, Melbourne, VIC, Australia., Lan P; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Institute for Advanced and Applied Chemical Synthesis, Jinan University, Jinan, China., Lessene G; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Department of Pharmacology and Therapeutics, University of Melbourne, Melbourne, VIC, Australia., Herold MJ; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia.; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia., Strasser A; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Spencer A; Australian Centre for Blood Diseases, Alfred Health-Monash University, Melbourne, VIC, Australia.; Department of Clinical Haematology, The Alfred Hospital, Melbourne, VIC, Australia.; Malignant Haematology and Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia., Grigoriadis G; School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Wei AH; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Australian Centre for Blood Diseases, Alfred Health-Monash University, Melbourne, VIC, Australia.; Department of Clinical Haematology, The Alfred Hospital, Melbourne, VIC, Australia.; Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., van Delft MF; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Roberts AW; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia. roberts@wehi.edu.au.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. roberts@wehi.edu.au.; Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. roberts@wehi.edu.au., Huang DCS; Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia. huang_d@wehi.edu.au.; Departments of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. huang_d@wehi.edu.au. |
| Source: | Cell death and differentiation [Cell Death Differ] 2025 Aug; Vol. 32 (8), pp. 1382-1396. Date of Electronic Publication: 2025 Apr 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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