Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles.
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| Title: | Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles. |
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| Authors: | Østergaard ME; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Carrer M; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Anderson BA; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Afetian M; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Bakooshli MA; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Santos JA; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Klein SK; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Capitanio J; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Freestone GC; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Tanowitz M; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Galindo-Murillo R; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Gaus HJ; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Dwyer CA; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Jackson M; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Jafar-Nejad P; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Rigo F; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Seth PP; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States., Gaynor KU; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Stanway SJ; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Urbonas L; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., St Denis MA; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Pellegrino S; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Bezerra GA; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Rigby M; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Gowans E; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Van Rietschoten K; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Beswick P; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Chen L; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Skynner MJ; Bicycle Therapeutics, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Swayze EE; Ionis Pharmaceuticals Inc., 2855 Gazelle Court, Carlsbad, CA 92010, United States. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2025 Apr 10; Vol. 53 (7). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1362-4962 |
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| DOI: | 10.1093/nar/gkaf270 |
