View in EDS

Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.

Saved in:
Bibliographic Details
Title: Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
Authors: Rezaei A; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany., Kocsis-Jutka V; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Gunes ZI; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany., Zeng Q; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany., Kislinger G; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Bauernschmitt F; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany., Isilgan HB; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Parisi LR; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA., Kaya T; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Franzenburg S; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Koppenbrink J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Knogler J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Arzberger T; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany., Farny D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Nuscher B; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Munich, Germany., Katona E; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany., Dhingra A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Yang C; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Gouna G; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany., LaClair KD; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Janjic A; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, Munich, Germany., Enard W; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, Munich, Germany., Zhou Q; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Hagan N; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA., Ofengeim D; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA., Beltrán E; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany., Gokce O; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.; Institute for Stroke and Dementia Research, University Hospital of Munich, LMU Munich, Munich, Germany., Simons M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany., Liebscher S; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany.; Institute of Neurobiochemistry, Medical University of Innsbruck, Innsbruck, Austria., Edbauer D; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. dieter.edbauer@dzne.de.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany. dieter.edbauer@dzne.de.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany. dieter.edbauer@dzne.de.
Source: Nature communications [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3442. Date of Electronic Publication: 2025 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40216746
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Rezaei+A%22">Rezaei A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kocsis-Jutka+V%22">Kocsis-Jutka V</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gunes+ZI%22">Gunes ZI</searchLink>; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zeng+Q%22">Zeng Q</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kislinger+G%22">Kislinger G</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bauernschmitt+F%22">Bauernschmitt F</searchLink>; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Isilgan+HB%22">Isilgan HB</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Parisi+LR%22">Parisi LR</searchLink>; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kaya+T%22">Kaya T</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Franzenburg+S%22">Franzenburg S</searchLink>; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Koppenbrink+J%22">Koppenbrink J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Knogler+J%22">Knogler J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Arzberger+T%22">Arzberger T</searchLink>; Center for Neuropathology and Prion Research, University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Farny+D%22">Farny D</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Nuscher+B%22">Nuscher B</searchLink>; Chair of Metabolic Biochemistry, Biomedical Center (BMC), Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Katona+E%22">Katona E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dhingra+A%22">Dhingra A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gouna+G%22">Gouna G</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22LaClair+KD%22">LaClair KD</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Janjic+A%22">Janjic A</searchLink>; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Enard+W%22">Enard W</searchLink>; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hagan+N%22">Hagan N</searchLink>; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ofengeim+D%22">Ofengeim D</searchLink>; Sanofi, Rare and Neurologic Diseases, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Beltrán+E%22">Beltrán E</searchLink>; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gokce+O%22">Gokce O</searchLink>; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.; Institute for Stroke and Dementia Research, University Hospital of Munich, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Simons+M%22">Simons M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Liebscher+S%22">Liebscher S</searchLink>; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany.; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig Maximilians University Munich, Munich, Germany.; Biomedical Center, Ludwig Maximilians University Munich, Munich, Germany.; Institute of Neurobiochemistry, Medical University of Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Edbauer+D%22">Edbauer D</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. dieter.edbauer@dzne.de.; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany. dieter.edbauer@dzne.de.; Ludwig-Maximilians-Universität (LMU) Munich, Graduate School of Systemic Neurosciences (GSN), Munich, Germany. dieter.edbauer@dzne.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3442. <i>Date of Electronic Publication: </i>2025 Apr 11.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40216746
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-025-58634-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3442
    Titles:
      – TitleFull: Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Rezaei A
      – PersonEntity:
          Name:
            NameFull: Kocsis-Jutka V
      – PersonEntity:
          Name:
            NameFull: Gunes ZI
      – PersonEntity:
          Name:
            NameFull: Zeng Q
      – PersonEntity:
          Name:
            NameFull: Kislinger G
      – PersonEntity:
          Name:
            NameFull: Bauernschmitt F
      – PersonEntity:
          Name:
            NameFull: Isilgan HB
      – PersonEntity:
          Name:
            NameFull: Parisi LR
      – PersonEntity:
          Name:
            NameFull: Kaya T
      – PersonEntity:
          Name:
            NameFull: Franzenburg S
      – PersonEntity:
          Name:
            NameFull: Koppenbrink J
      – PersonEntity:
          Name:
            NameFull: Knogler J
      – PersonEntity:
          Name:
            NameFull: Arzberger T
      – PersonEntity:
          Name:
            NameFull: Farny D
      – PersonEntity:
          Name:
            NameFull: Nuscher B
      – PersonEntity:
          Name:
            NameFull: Katona E
      – PersonEntity:
          Name:
            NameFull: Dhingra A
      – PersonEntity:
          Name:
            NameFull: Yang C
      – PersonEntity:
          Name:
            NameFull: Gouna G
      – PersonEntity:
          Name:
            NameFull: LaClair KD
      – PersonEntity:
          Name:
            NameFull: Janjic A
      – PersonEntity:
          Name:
            NameFull: Enard W
      – PersonEntity:
          Name:
            NameFull: Zhou Q
      – PersonEntity:
          Name:
            NameFull: Hagan N
      – PersonEntity:
          Name:
            NameFull: Ofengeim D
      – PersonEntity:
          Name:
            NameFull: Beltrán E
      – PersonEntity:
          Name:
            NameFull: Gokce O
      – PersonEntity:
          Name:
            NameFull: Simons M
      – PersonEntity:
          Name:
            NameFull: Liebscher S
      – PersonEntity:
          Name:
            NameFull: Edbauer D
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 04
              Text: 2025 Apr 11
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1