Molecular hyperselection for optimal choice of first-line targeted therapy independent of primary tumor sidedness: An exploratory analysis of the randomized FIRE-3 study performed in RAS wild-type metastatic colorectal cancer.
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| Title: | Molecular hyperselection for optimal choice of first-line targeted therapy independent of primary tumor sidedness: An exploratory analysis of the randomized FIRE-3 study performed in RAS wild-type metastatic colorectal cancer. |
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| Authors: | Weiss L; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany. Electronic address: Lena.Weiss@med.uni-muenchen.de., Stintzing S; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany., Stahler A; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany., Benedikt Westphalen C; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany; Comprehensive Cancer Center Munich, LMU Klinikum, University of Munich, Munich, Germany., von Weikersthal LF; Praxis für Hämatologie/Onkologie, MVZ St. Marien, Amberg, Germany., Decker T; Oncological Practice, Ravensburg, Germany., Kiani A; Department of Hematology and Oncology, Klinikum Bayreuth GmbH, Bayreuth, Germany and Comprehensive Cancer Center-EMN, Erlangen, Germany., Vehling-Kaiser U; Oncological Practice, Landshut, Germany., Al-Batran SE; Institute of Clinical Cancer Research at Krankenhaus Nordwest University Cancer Center, Frankfurt, Germany., Heintges T; Department of Medicine II, Rheinlandklinikum Neuss, Neuss, Germany., Lerchenmüller CA; Oncological Practice, Münster, Germany., Kahl C; Department of Haematology and Oncology, Städtisches Klinikum Magdeburg, Magdeburg, Germany; Department of Haematology, Oncology and Palliative Care, Klinikum Magdeburg gGmbH, Magdeburg, Germany; Department of Hematology, Oncology, and Palliative Care, University of Rostock, Rostock, Germany., Seipelt G; Department of Hematology, Oncology, and Palliative Care, University of Rostock, Rostock, Germany; Oncological Practice, Bad Soden, Germany., Kullmann F; Oncological Practice, Bad Soden, Germany; Department of Medicine I, Klinikum Weiden, Weiden, Germany., Heinrich K; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany., Holch JW; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany., Alig A; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany., Jung A; Department of Medicine I, Klinikum Weiden, Weiden, Germany; Institute of Pathology, University of Munich, Munich, Germany., Modest DP; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany., Heinemann V; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany; Comprehensive Cancer Center Munich, LMU Klinikum, University of Munich, Munich, Germany. |
| Source: | European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2025 May 15; Vol. 221, pp. 115399. Date of Electronic Publication: 2025 Apr 04. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40222201 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Molecular hyperselection for optimal choice of first-line targeted therapy independent of primary tumor sidedness: An exploratory analysis of the randomized FIRE-3 study performed in RAS wild-type metastatic colorectal cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Weiss+L%22">Weiss L</searchLink>; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany. Electronic address: Lena.Weiss@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Stintzing+S%22">Stintzing S</searchLink>; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Stahler+A%22">Stahler A</searchLink>; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Benedikt+Westphalen+C%22">Benedikt Westphalen C</searchLink>; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany; Comprehensive Cancer Center Munich, LMU Klinikum, University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22von+Weikersthal+LF%22">von Weikersthal LF</searchLink>; Praxis für Hämatologie/Onkologie, MVZ St. Marien, Amberg, Germany.<br /><searchLink fieldCode="AU" term="%22Decker+T%22">Decker T</searchLink>; Oncological Practice, Ravensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kiani+A%22">Kiani A</searchLink>; Department of Hematology and Oncology, Klinikum Bayreuth GmbH, Bayreuth, Germany and Comprehensive Cancer Center-EMN, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Vehling-Kaiser+U%22">Vehling-Kaiser U</searchLink>; Oncological Practice, Landshut, Germany.<br /><searchLink fieldCode="AU" term="%22Al-Batran+SE%22">Al-Batran SE</searchLink>; Institute of Clinical Cancer Research at Krankenhaus Nordwest University Cancer Center, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Heintges+T%22">Heintges T</searchLink>; Department of Medicine II, Rheinlandklinikum Neuss, Neuss, Germany.<br /><searchLink fieldCode="AU" term="%22Lerchenmüller+CA%22">Lerchenmüller CA</searchLink>; Oncological Practice, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Kahl+C%22">Kahl C</searchLink>; Department of Haematology and Oncology, Städtisches Klinikum Magdeburg, Magdeburg, Germany; Department of Haematology, Oncology and Palliative Care, Klinikum Magdeburg gGmbH, Magdeburg, Germany; Department of Hematology, Oncology, and Palliative Care, University of Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Seipelt+G%22">Seipelt G</searchLink>; Department of Hematology, Oncology, and Palliative Care, University of Rostock, Rostock, Germany; Oncological Practice, Bad Soden, Germany.<br /><searchLink fieldCode="AU" term="%22Kullmann+F%22">Kullmann F</searchLink>; Oncological Practice, Bad Soden, Germany; Department of Medicine I, Klinikum Weiden, Weiden, Germany.<br /><searchLink fieldCode="AU" term="%22Heinrich+K%22">Heinrich K</searchLink>; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Holch+JW%22">Holch JW</searchLink>; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Alig+A%22">Alig A</searchLink>; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Jung+A%22">Jung A</searchLink>; Department of Medicine I, Klinikum Weiden, Weiden, Germany; Institute of Pathology, University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Modest+DP%22">Modest DP</searchLink>; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Cancer Immunology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Heinemann+V%22">Heinemann V</searchLink>; Department of Medicine III, LMU Klinikum, University of Munich, Munich, Germany; Comprehensive Cancer Center Munich, LMU Klinikum, University of Munich, Munich, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229005373%22">European journal of cancer (Oxford, England : 1990)</searchLink> [Eur J Cancer] 2025 May 15; Vol. 221, pp. 115399. <i>Date of Electronic Publication: </i>2025 Apr 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9005373 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0852 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209598049%22">09598049 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40222201 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejca.2025.115399 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 115399 Titles: – TitleFull: Molecular hyperselection for optimal choice of first-line targeted therapy independent of primary tumor sidedness: An exploratory analysis of the randomized FIRE-3 study performed in RAS wild-type metastatic colorectal cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Weiss L – PersonEntity: Name: NameFull: Stintzing S – PersonEntity: Name: NameFull: Stahler A – PersonEntity: Name: NameFull: Benedikt Westphalen C – PersonEntity: Name: NameFull: von Weikersthal LF – PersonEntity: Name: NameFull: Decker T – PersonEntity: Name: NameFull: Kiani A – PersonEntity: Name: NameFull: Vehling-Kaiser U – PersonEntity: Name: NameFull: Al-Batran SE – PersonEntity: Name: NameFull: Heintges T – PersonEntity: Name: NameFull: Lerchenmüller CA – PersonEntity: Name: NameFull: Kahl C – PersonEntity: Name: NameFull: Seipelt G – PersonEntity: Name: NameFull: Kullmann F – PersonEntity: Name: NameFull: Heinrich K – PersonEntity: Name: NameFull: Holch JW – PersonEntity: Name: NameFull: Alig A – PersonEntity: Name: NameFull: Jung A – PersonEntity: Name: NameFull: Modest DP – PersonEntity: Name: NameFull: Heinemann V IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2025 May 15 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1879-0852 Numbering: – Type: volume Value: 221 Titles: – TitleFull: European journal of cancer (Oxford, England : 1990) Type: main |
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