Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation.
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| Title: | Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation. |
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| Authors: | Mujtaba MA; Department of Pharmaceutics, Faculty of Pharmacy, Northern Border University, Arar, Saudi Arabia.; Center for Health Research, Northern Border University, Arar, Saudi Arabia., Rashid MA; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia., Godbole MD; Department of Pharmaceutical Analysis, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India., Alhamhoom Y; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Saudi Arabia., Shende DS; Department of Pharmaceutical Analysis, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India., Alshehri S; Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia., Akbar MJ; Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Kaleem M; Department of Pharmacology, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India., Mahajan UN; Department of Pharmaceutical Analysis, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India., Shahzad N; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2025 Mar 28; Vol. 16, pp. 1577331. Date of Electronic Publication: 2025 Mar 28 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1663-9812 |
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| DOI: | 10.3389/fphar.2025.1577331 |
