Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): update to study protocol and addition of a statistical analysis plan and health economic analysis plan for a randomised controlled surgical trial.
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| Title: | Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): update to study protocol and addition of a statistical analysis plan and health economic analysis plan for a randomised controlled surgical trial. |
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| Authors: | Lee CN; Department of Ophthalmology, King's College Hospital, London, UK., Desai R; Department of Ophthalmology, King's College Hospital, London, UK., Ramazzotto L; Faculty of Life Sciences and Medicine, King's College London, London, UK., Wafa H; Population Health Sciences, Faculty and Life Science and Medicine, King's College London, London, UK., Wang Y; Population Health Sciences, Faculty and Life Science and Medicine, King's College London, London, UK., Bunce C; The London School of Hygiene and Tropical Medicine, London, UK., Doungsong K; Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, Wales., Ezeofor V; Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, Wales., Edwards RT; Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, Wales., Lois N; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, Northern Ireland., Steel DH; Bioscience Institute, Newcastle University, Newcastle, UK., Peto T; Network of Ophthalmic Reading Centres UK, Queen's University, Belfast, Northern Ireland., Hillenkamp J; Eye Clinic, University of Wurzburg, Wurzburg, Germany., van Meurs JC; Rotterdam Eye Hospital and Erasmus Medical Centre, Rotterdam, the Netherlands., Reeves BC; University of Bristol, Bristol, UK., Jackson TL; Faculty of Life Sciences and Medicine, King's College London, London, UK. t.jackson1@nhs.net. |
| Source: | Trials [Trials] 2025 Apr 14; Vol. 26 (1), pp. 131. Date of Electronic Publication: 2025 Apr 14. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1745-6215 |
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| DOI: | 10.1186/s13063-025-08727-8 |
