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Essential lipids enrich membrane-associated condensates to rescue synaptic morpho-functional deficits in a mouse model of autism.

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Title: Essential lipids enrich membrane-associated condensates to rescue synaptic morpho-functional deficits in a mouse model of autism.
Authors: Arsenault J; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Kong T; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Saghian R; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Weng OY; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Pathak SS; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA., Yang C; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Chao OY; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA., Rakhaminov G; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Forman-Kay JD; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Ditlev JA; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada; Program in Cell Biology, SickKids Research Institute, Toronto, ON M5G 1X8, Canada. Electronic address: jonathon.ditlev@sickkids.ca., Yang YM; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA. Electronic address: ymyang@umn.edu., Wang LY; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: luyang.wang@utoronto.ca.
Source: Cell reports [Cell Rep] 2025 May 27; Vol. 44 (5), pp. 115573. Date of Electronic Publication: 2025 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Essential lipids enrich membrane-associated condensates to rescue synaptic morpho-functional deficits in a mouse model of autism.
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  Data: <searchLink fieldCode="AU" term="%22Arsenault+J%22">Arsenault J</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Kong+T%22">Kong T</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Saghian+R%22">Saghian R</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Weng+OY%22">Weng OY</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Pathak+SS%22">Pathak SS</searchLink>; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Chao+OY%22">Chao OY</searchLink>; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA.<br /><searchLink fieldCode="AU" term="%22Rakhaminov+G%22">Rakhaminov G</searchLink>; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Forman-Kay+JD%22">Forman-Kay JD</searchLink>; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Ditlev+JA%22">Ditlev JA</searchLink>; Program in Molecular Medicine, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada; Program in Cell Biology, SickKids Research Institute, Toronto, ON M5G 1X8, Canada. Electronic address: jonathon.ditlev@sickkids.ca.<br /><searchLink fieldCode="AU" term="%22Yang+YM%22">Yang YM</searchLink>; Department of Biomedical Sciences, University of Minnesota Medical School, 1035 University Drive, Duluth, MN 55812, USA. Electronic address: ymyang@umn.edu.<br /><searchLink fieldCode="AU" term="%22Wang+LY%22">Wang LY</searchLink>; Program in Neurosciences & Mental Health, SickKids Research Institute, Toronto, ON M5G 1X8, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: luyang.wang@utoronto.ca.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2025 May 27; Vol. 44 (5), pp. 115573. <i>Date of Electronic Publication: </i>2025 Apr 14.
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