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Outcomes of PLAT-02 and PLAT-03: evaluating CD19 CAR T-cell therapy and CD19-expressing T-APC support in pediatric B-ALL.

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Title: Outcomes of PLAT-02 and PLAT-03: evaluating CD19 CAR T-cell therapy and CD19-expressing T-APC support in pediatric B-ALL.
Authors: Annesley C; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA., Seidel K; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Wu Q; Clinical Biostatistics, Fred Hutchinson Cancer Center, Seattle, WA., Summers C; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA., Wayne AS; Department of Pediatrics, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA., Pulsipher MA; Division of Pediatric Hematology and Oncology, Intermountain Primary Children's Hospital, Huntsman Cancer Institute, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT., Agrawal AK; Division of Oncology, University of California San Francisco Benioff Children's Hospitals, Oakland, CA., Brown CT; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Mgebroff S; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Lindgren C; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Rawlings-Rhea S; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Huang W; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Wilson AL; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Jensen MC; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA., Park JR; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN., Gardner RA; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
Source: Blood [Blood] 2025 Aug 14; Vol. 146 (7), pp. 789-801.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Outcomes of PLAT-02 and PLAT-03: evaluating CD19 CAR T-cell therapy and CD19-expressing T-APC support in pediatric B-ALL.
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  Data: <searchLink fieldCode="AU" term="%22Annesley+C%22">Annesley C</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Seidel+K%22">Seidel K</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Clinical Biostatistics, Fred Hutchinson Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Summers+C%22">Summers C</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Wayne+AS%22">Wayne AS</searchLink>; Department of Pediatrics, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Pulsipher+MA%22">Pulsipher MA</searchLink>; Division of Pediatric Hematology and Oncology, Intermountain Primary Children's Hospital, Huntsman Cancer Institute, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Agrawal+AK%22">Agrawal AK</searchLink>; Division of Oncology, University of California San Francisco Benioff Children's Hospitals, Oakland, CA.<br /><searchLink fieldCode="AU" term="%22Brown+CT%22">Brown CT</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Mgebroff+S%22">Mgebroff S</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Lindgren+C%22">Lindgren C</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Rawlings-Rhea+S%22">Rawlings-Rhea S</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Wilson+AL%22">Wilson AL</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Jensen+MC%22">Jensen MC</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Park+JR%22">Park JR</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Gardner+RA%22">Gardner RA</searchLink>; Seattle Children's Therapeutics, Seattle Childrens Hospital, Seattle, WA.; Department of Pediatrics, University of Washington, Seattle, WA.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
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        Value: 10.1182/blood.2025028359
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              Text: 2025 Aug 14
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