Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development.

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Title: Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development.
Authors: Siegal EZ; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Schoevers JMH; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Terstappen J; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Delemarre EM; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Johnston SL; Virtus Respiratory Research Ltd, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., van Beek LF; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., Bogaert D; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK., Chiu C; Virtus Respiratory Research Ltd, London, UK., Diavatopoulos DA; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands., Ferreira DM; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Gordon SB; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Hayden FG; Division of infectious Diseases and International Health, University of Virginia, School of Medicine, Charlottesville, VA, USA., de Jonge MI; Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., McCall MBB; Radboud Center for Infectious Diseases, Radboud university medical Center, Nijmegen, The Netherlands., McShane HI; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Minassian AM; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Biochemistry, University of Oxford, Oxford, UK., Openshaw PJM; National Heart and Lung Institute, Imperial College London, London, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, The NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Sattabongkot J; Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Read RC; Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK., Troelstra A; Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands., Viveen MC; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Wilder-Smith A; Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany., van Wijk M; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands., Bont LJ; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.; Respiratory Syncytial Virus Network (ReSViNET), Utrecht, The Netherlands., Mazur NI; Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Center for Translational Immunology (CTI), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. n.i.mazur@umcutrecht.nl.; Department of Pediatrics, St. Antonius Hospital, Nieuwegein, The Netherlands. n.i.mazur@umcutrecht.nl.
Source: NPJ vaccines [NPJ Vaccines] 2025 Apr 15; Vol. 10 (1), pp. 70. Date of Electronic Publication: 2025 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2059-0105
DOI:10.1038/s41541-025-01125-w