Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function.
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| Title: | Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function. |
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| Authors: | Fleming SM; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States., Scott S; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States., Hamad EJ; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States., Herman DE; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, United States., Holden JG; Department of Psychology, University of Cincinnati, Cincinnati, OH, United States., Yan L; Department of Psychology, Michigan State University, East Lansing, MI, United States., Linning-Duffy K; Department of Psychology, Michigan State University, East Lansing, MI, United States., Kemp CJ; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Patterson JR; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Miller KM; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Kubik M; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Kuhn N; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Stoll AC; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Duffy MF; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Steece-Collier K; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Cole-Strauss A; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Lipton JW; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States., Luk KC; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, United States., Sortwell CE; Department of Translational Neuroscience, Michigan State University, Grand Rapids, MI, United States. |
| Source: | Frontiers in neuroscience [Front Neurosci] 2025 Apr 01; Vol. 19, pp. 1556447. Date of Electronic Publication: 2025 Apr 01 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1662-4548 |
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| DOI: | 10.3389/fnins.2025.1556447 |
