Autophagy induction enhances homologous recombination-associated CRISPR-Cas9 gene editing.

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Title: Autophagy induction enhances homologous recombination-associated CRISPR-Cas9 gene editing.
Authors: Nam HJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, Daejeon 34113, Republic of Korea., Han JH; Department of Chemistry, Hanyang University, Seoul 04673, Republic of Korea., Yu J; Medical Research Center of Genomic Medicine Institute, Seoul National University College of Medicine, Seoul 03080, Republic of Korea., Cho CS; Fight Against Angiogenesis-Related Blindness (FARB) Laboratory, Biomedical Research Institute, Seoul National University, Seoul 03080, Republic of Korea., Kim D; Department of Anatomy, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea., Kim YE; Center for Bioanalysis, Division of Chemical and Medical Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Republic of Korea., Kim MJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.; Department of Medicinal Chemistry and Pharmacology, University of Science and Technology, Daejeon 34113, Republic of Korea., Kim JH; Fight Against Angiogenesis-Related Blindness (FARB) Laboratory, Biomedical Research Institute, Seoul National University, Seoul 03080, Republic of Korea.; Global Excellence Center for Gene & Cell Therapy (GEC-GCT), Seoul National University Hospital, Seoul 03080, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.; Department of Ophthalmology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea., Jo DH; Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea., Bae S; Medical Research Center of Genomic Medicine Institute, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Source: Nucleic acids research [Nucleic Acids Res] 2025 Apr 10; Vol. 53 (7).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1362-4962
DOI:10.1093/nar/gkaf258