Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review.

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Title: Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review.
Authors: Meshkat S; Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Ontario, Canada., Malik G; Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Ontario, Canada., Zeifman RJ; NYU Center for Psychedelic Medicine, NYU Grossman School of Medicine, New York, NY, USA; Center for Psychedelic Research, Imperial College London, London, UK., Swainson J; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada., Balachandra K; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada., Reichelt AC; Department of Physiology and Pharmacology, Western University, London, Canada; School of Biomedicine, Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia., Zhang Y; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada., Burback L; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada., Winkler O; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada., Greenshaw A; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada; Neuroscience and Mental Health Institute (NMHI), University of Alberta, Edmonton, Alberta, Canada., Vermetten E; Department of Psychiatry, Leiden University Medical Center, Leiden, Netherlands., Mayo LM; Department of Psychiatry, Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada., Tanguay R; Department of Psychiatry, Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada., Jetly R; The Institute of Mental Health Research, University of Ottawa, Royal Ottawa Hospital, Ontario, Canada., Bhat V; Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address: venkat.bhat@utoronto.ca.
Source: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2025 Jun; Vol. 173, pp. 106163. Date of Electronic Publication: 2025 Apr 15.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Pergamon Press Country of Publication: United States NLM ID: 7806090 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7528 (Electronic) Linking ISSN: 01497634 NLM ISO Abbreviation: Neurosci Biobehav Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-7528
DOI:10.1016/j.neubiorev.2025.106163