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Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease.

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Title: Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease.
Authors: Mengel D; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany., Soter E; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Ott JM; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Wacker M; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Leyva A; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Psychiatry and Psychotherapy, Charitéplatz 1, 10117, Berlin, Germany., Hellmann-Regen J; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany., Schneider LS; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Psychiatry and Psychotherapy, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Experimental and Clinical Research Center (ECRC), Lindenberger Weg 80, 13125, Berlin, Germany., Wang X; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany.; School of Medicine, Technical University of Munich, Department of Psychiatry and Psychotherapy, Ismaninger Str. 22, 81675, Munich, Germany.; University of Edinburgh and UK Dementia Research Institute (UK DRI), Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Spruth E; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany., Altenstein S; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Fliessbach K; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Wiltfang J; German Center for Neurodegenerative Diseases (DZNE), Von-Siebold-Straße 3a, 37075, Göttingen, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Campus Universitário de Santiago, 3810-193, Aveiro, Portugal., Hansen N; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany., Rostamzadeh A; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany., Incesoy EI; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany.; Department of Psychiatry and Psychotherapy, University Clinic Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany., Buerger K; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU, Feodor-Lynen-Str. 17, 81377, Munich, Germany., Janowitz D; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany., Ewers M; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU, Feodor-Lynen-Str. 17, 81377, Munich, Germany., Perneczky R; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU, Nussbaumstraße 7, 80336, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, St. Mary's Campus, Norfolk Place, London, W2 1PG, UK., Rauchmann B; Department of Psychiatry and Psychotherapy, University Hospital, LMU, Nussbaumstraße 7, 80336, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Department of Neuroradiology, University Hospital LMU, Marchioninistraße 15, 81377, Munich, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Straße 20, 18147, Rostock, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Straße 20, 18147, Rostock, Germany., Laske C; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Sodenkamp S; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Calwerstraße 14, 72076, Tübingen, Germany., Spottke A; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Neurology, University of Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Brustkern J; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany., Brosseron F; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Stark M; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany., Kleineidam L; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Shao K; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Neurology, XuanWu Hospital of Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China., Lüsebrink F; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany., Yakupov R; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany., Schmid M; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Institute for Medical Biometry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany., Hetzer S; Berlin Center for Advanced Neuroimaging, Charité - Universitätsmedizin Berlin, Philippstraße 13, 10115, Berlin, Germany., Dechent P; MR-Research in Neurosciences, Department of Cognitive Neurology, Georg-August-University Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany., Scheffler K; Department for Biomedical Magnetic Resonance, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany., Berron D; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Sölvegatan 17, 223 62, Lund, Sweden., Jessen F; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Straße 26, 50931, Cologne, Germany., Synofzik M; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany. matthis.synofzik@uni-tuebingen.de.; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany. matthis.synofzik@uni-tuebingen.de.
Corporate Authors: DELCODE study group
Source: Molecular psychiatry [Mol Psychiatry] 2025 Jul; Vol. 30 (7), pp. 3150-3159. Date of Electronic Publication: 2025 Apr 18.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Mengel+D%22">Mengel D</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Soter+E%22">Soter E</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ott+JM%22">Ott JM</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wacker+M%22">Wacker M</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Leyva+A%22">Leyva A</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Psychiatry and Psychotherapy, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hellmann-Regen+J%22">Hellmann-Regen J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+LS%22">Schneider LS</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Psychiatry and Psychotherapy, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Experimental and Clinical Research Center (ECRC), Lindenberger Weg 80, 13125, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Charité - Universitätsmedizin Berlin, Department of Psychiatry and Neurosciences, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany.; School of Medicine, Technical University of Munich, Department of Psychiatry and Psychotherapy, Ismaninger Str. 22, 81675, Munich, Germany.; University of Edinburgh and UK Dementia Research Institute (UK DRI), Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.<br /><searchLink fieldCode="AU" term="%22Spruth+E%22">Spruth E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Altenstein+S%22">Altenstein S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, 10117, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Fliessbach+K%22">Fliessbach K</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Von-Siebold-Straße 3a, 37075, Göttingen, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Campus Universitário de Santiago, 3810-193, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Hansen+N%22">Hansen N</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Rostamzadeh+A%22">Rostamzadeh A</searchLink>; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Glanz+W%22">Glanz W</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Incesoy+EI%22">Incesoy EI</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Leipziger Str. 44, 39120, Magdeburg, Germany.; Department of Psychiatry and Psychotherapy, University Clinic Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Buerger+K%22">Buerger K</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU, Feodor-Lynen-Str. 17, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Janowitz+D%22">Janowitz D</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ewers+M%22">Ewers M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU, Feodor-Lynen-Str. 17, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Perneczky+R%22">Perneczky R</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU, Nussbaumstraße 7, 80336, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Feodor-Lynen-Str. 17, 81377, Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, St. Mary's Campus, Norfolk Place, London, W2 1PG, UK.<br /><searchLink fieldCode="AU" term="%22Rauchmann+B%22">Rauchmann B</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, LMU, Nussbaumstraße 7, 80336, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Department of Neuroradiology, University Hospital LMU, Marchioninistraße 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Teipel+S%22">Teipel S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Straße 20, 18147, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Kilimann+I%22">Kilimann I</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Straße 20, 18147, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Laske+C%22">Laske C</searchLink>; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sodenkamp+S%22">Sodenkamp S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Calwerstraße 14, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Spottke+A%22">Spottke A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Neurology, University of Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Brustkern+J%22">Brustkern J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Brosseron+F%22">Brosseron F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Stark+M%22">Stark M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kleineidam+L%22">Kleineidam L</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Shao+K%22">Shao K</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Neurology, XuanWu Hospital of Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.<br /><searchLink fieldCode="AU" term="%22Lüsebrink+F%22">Lüsebrink F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Yakupov+R%22">Yakupov R</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, 18147, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+M%22">Schmid M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Institute for Medical Biometry, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hetzer+S%22">Hetzer S</searchLink>; Berlin Center for Advanced Neuroimaging, Charité - Universitätsmedizin Berlin, Philippstraße 13, 10115, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Dechent+P%22">Dechent P</searchLink>; MR-Research in Neurosciences, Department of Cognitive Neurology, Georg-August-University Göttingen, Von-Siebold-Straße 3a, 37075, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Scheffler+K%22">Scheffler K</searchLink>; Department for Biomedical Magnetic Resonance, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Berron+D%22">Berron D</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, 39120, Magdeburg, Germany.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Sölvegatan 17, 223 62, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Sigmund-Freud-Straße 27, 53127, Bonn, Germany.; Department of Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Straße 26, 50931, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Synofzik+M%22">Synofzik M</searchLink>; Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany. matthis.synofzik@uni-tuebingen.de.; German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Otfried-Müller-Straße 27, 72076, Tübingen, Germany. matthis.synofzik@uni-tuebingen.de.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2025 Jul; Vol. 30 (7), pp. 3150-3159. <i>Date of Electronic Publication: </i>2025 Apr 18.
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  Data: Journal Article; Multicenter Study
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40247130
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41380-025-03021-0
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
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        StartPage: 3150
    Titles:
      – TitleFull: Blood biomarkers confirm subjective cognitive decline (SCD) as a distinct molecular and clinical stage within the NIA-AA framework of Alzheimer´s disease.
        Type: main
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            – D: 01
              M: 07
              Text: 2025 Jul
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5578
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              Value: 30
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Molecular psychiatry
              Type: main
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