Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway.
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| Title: | Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway. |
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| Authors: | Tabaa MME; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt. Electronic address: manar.eltabaa@esri.usc.edu.eg., Harty MEE; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt., Mohsen M; Pharmacology and Toxicology Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt., Rashad E; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Egypt., Negm WA; Pharmacognosy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Elmorshedy K; Anatomy Department, Faculty of Medicine, Tanta University, Tanta, Egypt., Abu-Risha SE; Pharmacology & Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt. |
| Source: | The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Aug; Vol. 142, pp. 109934. Date of Electronic Publication: 2025 Apr 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1873-4847 |
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| DOI: | 10.1016/j.jnutbio.2025.109934 |