Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway.
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| Title: | Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway. |
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| Authors: | Tabaa MME; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt. Electronic address: manar.eltabaa@esri.usc.edu.eg., Harty MEE; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt., Mohsen M; Pharmacology and Toxicology Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt., Rashad E; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Egypt., Negm WA; Pharmacognosy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Elmorshedy K; Anatomy Department, Faculty of Medicine, Tanta University, Tanta, Egypt., Abu-Risha SE; Pharmacology & Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt. |
| Source: | The Journal of nutritional biochemistry [J Nutr Biochem] 2025 Aug; Vol. 142, pp. 109934. Date of Electronic Publication: 2025 Apr 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40258498 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tabaa+MME%22">Tabaa MME</searchLink>; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt. Electronic address: manar.eltabaa@esri.usc.edu.eg.<br /><searchLink fieldCode="AU" term="%22Harty+MEE%22">Harty MEE</searchLink>; Pharmacology & Environmental Toxicology, Environmental Studies & Research Institute (ESRI), University of Sadat City, Sadat City, Menoufia, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohsen+M%22">Mohsen M</searchLink>; Pharmacology and Toxicology Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.<br /><searchLink fieldCode="AU" term="%22Rashad+E%22">Rashad E</searchLink>; Cytology and Histology Department, Faculty of Veterinary Medicine, Cairo University, Egypt.<br /><searchLink fieldCode="AU" term="%22Negm+WA%22">Negm WA</searchLink>; Pharmacognosy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22Elmorshedy+K%22">Elmorshedy K</searchLink>; Anatomy Department, Faculty of Medicine, Tanta University, Tanta, Egypt.<br /><searchLink fieldCode="AU" term="%22Abu-Risha+SE%22">Abu-Risha SE</searchLink>; Pharmacology & Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229010081%22">The Journal of nutritional biochemistry</searchLink> [J Nutr Biochem] 2025 Aug; Vol. 142, pp. 109934. <i>Date of Electronic Publication: </i>2025 Apr 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9010081 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4847 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209552863%22">09552863 </searchLink><i>NLM ISO Abbreviation: </i>J Nutr Biochem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40258498 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jnutbio.2025.109934 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 109934 Titles: – TitleFull: Integrating network pharmacology and in vivo pharmacological validation to explore the gastroprotective mechanism of Sotetsuflavone against indomethacin-induced gastric ulcer in rats: Involvement of JAK2/STAT3 pathway. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tabaa MME – PersonEntity: Name: NameFull: Harty MEE – PersonEntity: Name: NameFull: Mohsen M – PersonEntity: Name: NameFull: Rashad E – PersonEntity: Name: NameFull: Negm WA – PersonEntity: Name: NameFull: Elmorshedy K – PersonEntity: Name: NameFull: Abu-Risha SE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2025 Aug Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1873-4847 Numbering: – Type: volume Value: 142 Titles: – TitleFull: The Journal of nutritional biochemistry Type: main |
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