Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification.

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Title: Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification.
Authors: Harding RJ; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada., Xie Y; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32827, USA., Caron NS; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Findlay-Black H; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Lyu C; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Potluri N; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32827, USA., Chandrasekaran R; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada., Hayden MR; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Leavitt BR; Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC, V5Z 4H4, Canada., Langbehn DR; Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Southwell AL; Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL, 32827, USA. amber.southwell@ucf.edu.
Source: Biomarker research [Biomark Res] 2025 Apr 21; Vol. 13 (1), pp. 63. Date of Electronic Publication: 2025 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101607860 Publication Model: Electronic Cited Medium: Print ISSN: 2050-7771 (Print) Linking ISSN: 20507771 NLM ISO Abbreviation: Biomark Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2050-7771
DOI:10.1186/s40364-025-00772-4