Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis.

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Title: Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis.
Authors: Zhou LY; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China., Wang XB; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Chen XQ; Department of Otolaryngology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Li R; Department of Rehabilitation Medicine, Traditional Chinese Medicine Hospital of LuAn, Luan, China., Yu BB; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China., Pan MX; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China., Fang L; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China., Li J; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China., Cui XJ; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Yao M; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Lu X; Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Apr 07; Vol. 16, pp. 1538879. Date of Electronic Publication: 2025 Apr 07 (Print Publication: 2025).
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1538879