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Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism.

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Title: Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism.
Authors: Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan. wtrshh9@gmail.com., Akasaka H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan., Jordan PA; Lassogen Inc., San Diego, CA, USA., Lechner A; Lassogen Inc., San Diego, CA, USA., Okada BK; Lassogen Inc., San Diego, CA, USA., Costa Machado da Cruz G; Lassogen Inc., San Diego, CA, USA., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan., Tanaka T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan., Kawahara R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan., Chaudhari R; Research Informatics, Eurofins Panlabs, Inc., Saint Charles, MO, USA., Masamune H; Lassogen Inc., San Diego, CA, USA., Burk MJ; Lassogen Inc., San Diego, CA, USA. mburk@lassogen.com., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.
Source: Nature communications [Nat Commun] 2025 Apr 22; Vol. 16 (1), pp. 3446. Date of Electronic Publication: 2025 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structure of a lasso peptide bound ET<subscript>B</subscript> receptor provides insights into the mechanism of GPCR inverse agonism.
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  Data: <searchLink fieldCode="AU" term="%22Shihoya+W%22">Shihoya W</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan. wtrshh9@gmail.com.<br /><searchLink fieldCode="AU" term="%22Akasaka+H%22">Akasaka H</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Jordan+PA%22">Jordan PA</searchLink>; Lassogen Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lechner+A%22">Lechner A</searchLink>; Lassogen Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Okada+BK%22">Okada BK</searchLink>; Lassogen Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Costa+Machado+da+Cruz+G%22">Costa Machado da Cruz G</searchLink>; Lassogen Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sano+FK%22">Sano FK</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahara+R%22">Kawahara R</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Chaudhari+R%22">Chaudhari R</searchLink>; Research Informatics, Eurofins Panlabs, Inc., Saint Charles, MO, USA.<br /><searchLink fieldCode="AU" term="%22Masamune+H%22">Masamune H</searchLink>; Lassogen Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Burk+MJ%22">Burk MJ</searchLink>; Lassogen Inc., San Diego, CA, USA. mburk@lassogen.com.<br /><searchLink fieldCode="AU" term="%22Nureki+O%22">Nureki O</searchLink>; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-Ku, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Apr 22; Vol. 16 (1), pp. 3446. <i>Date of Electronic Publication: </i>2025 Apr 22.
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