SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity.
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| Title: | SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity. |
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| Authors: | Hou G; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Beatty W; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Ren L; Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, USA.; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute of Research, VA Palo Alto Health Care System, Palo Alto, CA, USA.; School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China., Ooi YS; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA.; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore., Son J; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Zhu Y; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Sheng Q; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Huang W; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Li D; Division of Nephrology, Department of Medicine and Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO, USA., Liu C; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Welsh OL; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Sutherland DM; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Dermody TS; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Shen C; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Liu J; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Sibley LD; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Ding S; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. siyuan.ding@wustl.edu. |
| Source: | Nature communications [Nat Commun] 2025 Apr 22; Vol. 16 (1), pp. 3756. Date of Electronic Publication: 2025 Apr 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-59090-w |
