The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis.
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| Title: | The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis. |
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| Authors: | Soni H; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Tyagi S; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Mane K; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Shelke AM; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Kumar P; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Public Health Research Institute, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Kaya F; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA., Alland D; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Public Health Research Institute, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Zimmerman M; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA., Freundlich JS; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA., Nuermberger EL; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA. |
| Source: | Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Jun 04; Vol. 69 (6), pp. e0013025. Date of Electronic Publication: 2025 Apr 23. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40265947 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Soni+H%22">Soni H</searchLink>; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Tyagi+S%22">Tyagi S</searchLink>; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Mane+K%22">Mane K</searchLink>; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Shelke+AM%22">Shelke AM</searchLink>; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Public Health Research Institute, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Kaya+F%22">Kaya F</searchLink>; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Alland+D%22">Alland D</searchLink>; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Public Health Research Institute, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Zimmerman+M%22">Zimmerman M</searchLink>; Center for Discovery & Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Freundlich+JS%22">Freundlich JS</searchLink>; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University-New Jersey Medical School, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Nuermberger+EL%22">Nuermberger EL</searchLink>; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2025 Jun 04; Vol. 69 (6), pp. e0013025. <i>Date of Electronic Publication: </i>2025 Apr 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40265947 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1128/aac.00130-25 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0013025 Titles: – TitleFull: The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Soni H – PersonEntity: Name: NameFull: Tyagi S – PersonEntity: Name: NameFull: Mane K – PersonEntity: Name: NameFull: Shelke AM – PersonEntity: Name: NameFull: Kumar P – PersonEntity: Name: NameFull: Kaya F – PersonEntity: Name: NameFull: Alland D – PersonEntity: Name: NameFull: Zimmerman M – PersonEntity: Name: NameFull: Freundlich JS – PersonEntity: Name: NameFull: Nuermberger EL IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 06 Text: 2025 Jun 04 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1098-6596 Numbering: – Type: volume Value: 69 – Type: issue Value: 6 Titles: – TitleFull: Antimicrobial agents and chemotherapy Type: main |
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