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Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge.

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Title: Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge.
Authors: Mielke D; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Tuyishime M; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Kelkar NS; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH 03756, USA., Wang Y; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA., Parks R; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA., Santra S; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA., Rountree W; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA., Williams LD; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Peters T; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Eisel N; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Sawant S; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Zhang L; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Goodman D; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Jha S; Department of Surgery, Duke University, Durham, NC 27710, USA., Zalaquett A; Department of Surgery, Duke University, Durham, NC 27710, USA., Ramasubramanian P; Department of Surgery, Duke University, Durham, NC 27710, USA., Stanfield-Oakley S; Department of Surgery, Duke University, Durham, NC 27710, USA., Matyas G; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Beck Z; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Rao M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Ake J; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Denny TN; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA., Montefiori DC; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Ackerman ME; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Dartmouth College, Hanover, NH 03756, USA.; Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA 98104, USA., Tomaras GD; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Korber BT; T-6: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; New Mexico Consortium, Los Alamos, NM 87545, USA., Haynes BF; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA., Shen X; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA., Ferrari G; Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA.; Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.; Department of Surgery, Duke University, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Source: Vaccines [Vaccines (Basel)] 2025 Feb 24; Vol. 13 (3). Date of Electronic Publication: 2025 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629355 Publication Model: Electronic Cited Medium: Print ISSN: 2076-393X (Print) Linking ISSN: 2076393X NLM ISO Abbreviation: Vaccines (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2076-393X
DOI:10.3390/vaccines13030231