Polymer model integrates imaging and sequencing to reveal how nanoscale heterochromatin domains influence gene expression.
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| Title: | Polymer model integrates imaging and sequencing to reveal how nanoscale heterochromatin domains influence gene expression. |
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| Authors: | Vinayak V; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Basir R; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Golloshi R; Departments of Cell Biology, Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Giovanis Institute for Translational Cell Biology, Johns Hopkins Medicine, Baltimore, MD, USA., Toth J; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA., Sant'Anna L; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Bioengineering, Stanford University, Stanford, CA, USA., Lakadamyali M; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA.; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., McCord RP; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, USA., Shenoy VB; Center for Engineering Mechanobiology, University of Pennsylvania, Philadelphia, PA, USA. vshenoy@seas.upenn.edu.; Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA, USA. vshenoy@seas.upenn.edu. |
| Source: | Nature communications [Nat Commun] 2025 Apr 23; Vol. 16 (1), pp. 3816. Date of Electronic Publication: 2025 Apr 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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