Restoration of Shal/KV4 proteostasis and motor function in a Drosophila model of spinocerebellar ataxia type 19/22.

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Title: Restoration of Shal/KV4 proteostasis and motor function in a Drosophila model of spinocerebellar ataxia type 19/22.
Authors: Hsiao CT; Department of Neurology, Taipei Veterans General Hospital, Taipei, 112, Taiwan.; Department of Neurology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan.; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan., Fu SJ; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan.; Institute of Anatomy and Cell Biology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan., Cheng KM; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan., Lo H; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan., Tang CY; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan. tang@ntu.edu.tw., Chan CC; Department of Physiology, College of Medicine, National Taiwan University, Taipei, 100, Taiwan. chancc1@ntu.edu.tw., Jeng CJ; Institute of Anatomy and Cell Biology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan. cjjeng@nycu.edu.tw.; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, 112, Taiwan. cjjeng@nycu.edu.tw.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Apr 28; Vol. 82 (1), pp. 181. Date of Electronic Publication: 2025 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-05711-y