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Antibiotic-Loaded Polymer-Calcium Phosphate Scaffold for Treating Orthopedic Device-Related Infection in a Rabbit Segmental Bone Defect Model.

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Title: Antibiotic-Loaded Polymer-Calcium Phosphate Scaffold for Treating Orthopedic Device-Related Infection in a Rabbit Segmental Bone Defect Model.
Authors: Buchholz T; AO Research Institute Davos, Davos, Switzerland., Siverino C; AO Research Institute Davos, Davos, Switzerland., Moriarty TF; AO Research Institute Davos, Davos, Switzerland., Sheehy EJ; AO Research Institute Davos, Davos, Switzerland.; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, Dublin, Ireland., O'Brien FJ; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, Dublin, Ireland., Nehrbass D; AO Research Institute Davos, Davos, Switzerland., Arveladze S; AO Research Institute Davos, Davos, Switzerland., Constant C; AO Research Institute Davos, Davos, Switzerland., Elsayed SH; Surgical Discovery Centre, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.; Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine (CAVM), United Arab Emirates University (UAEU), Al Ain, Abu Dhabi, UAE.; Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt., Yan M; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA., Awad HA; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA., Zeiter S; AO Research Institute Davos, Davos, Switzerland., Allen MJ; Surgical Discovery Centre, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Source: Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2025 May; Vol. 113 (5), pp. e37917.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234237 Publication Model: Print Cited Medium: Internet ISSN: 1552-4965 (Electronic) Linking ISSN: 15493296 NLM ISO Abbreviation: J Biomed Mater Res A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antibiotic-Loaded Polymer-Calcium Phosphate Scaffold for Treating Orthopedic Device-Related Infection in a Rabbit Segmental Bone Defect Model.
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  Data: <searchLink fieldCode="AU" term="%22Buchholz+T%22">Buchholz T</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Siverino+C%22">Siverino C</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Moriarty+TF%22">Moriarty TF</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sheehy+EJ%22">Sheehy EJ</searchLink>; AO Research Institute Davos, Davos, Switzerland.; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Brien+FJ%22">O'Brien FJ</searchLink>; Tissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Advanced Materials and Bioengineering Research (AMBER) Centre, Royal College of Surgeons in Ireland & Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Nehrbass+D%22">Nehrbass D</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Arveladze+S%22">Arveladze S</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Constant+C%22">Constant C</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Elsayed+SH%22">Elsayed SH</searchLink>; Surgical Discovery Centre, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.; Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine (CAVM), United Arab Emirates University (UAEU), Al Ain, Abu Dhabi, UAE.; Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Yan+M%22">Yan M</searchLink>; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.<br /><searchLink fieldCode="AU" term="%22Awad+HA%22">Awad HA</searchLink>; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.<br /><searchLink fieldCode="AU" term="%22Zeiter+S%22">Zeiter S</searchLink>; AO Research Institute Davos, Davos, Switzerland.<br /><searchLink fieldCode="AU" term="%22Allen+MJ%22">Allen MJ</searchLink>; Surgical Discovery Centre, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
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