GLPG2737, a CFTR Inhibitor, Prevents Cyst Growth in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease.
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| Title: | GLPG2737, a CFTR Inhibitor, Prevents Cyst Growth in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease. |
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| Authors: | Dumont V; Translational Science, Galapagos SASU, Romainville, France., Meurisse S; In Vivo Pharmacology, Galapagos SASU, Romainville, France., Verdonck K; Kidney Therapeutic Area Group, Galapagos NV, Mechelen, Belgium., Salgues V; Translational Science, Galapagos SASU, Romainville, France., Robert T; Histology, Galapagos SASU, Romainville, France., Anquetil F; Histology, Galapagos SASU, Romainville, France., Delachaume C; In Vivo Pharmacology, Galapagos SASU, Romainville, France., Blanqué R; Translational Science, Galapagos SASU, Romainville, France., Liekens D; Kidney Therapeutic Area Group, Galapagos NV, Mechelen, Belgium., Huang Y; Mayo Translational Polycystic Kidney Disease Center, Mayo Clinic, Rochester, Minnesota, USA.; Department of Biochemistry and Molecular Biology, School of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Hu J; Mayo Translational Polycystic Kidney Disease Center, Mayo Clinic, Rochester, Minnesota, USA.; Department of Biochemistry and Molecular Biology, School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.; Division of Nephrology and Hypertension, School of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Harris PC; Mayo Translational Polycystic Kidney Disease Center, Mayo Clinic, Rochester, Minnesota, USA.; Department of Biochemistry and Molecular Biology, School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.; Division of Nephrology and Hypertension, School of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Nakhlé J; Translational Research, Galapagos SASU, Romainville, France., Conrath K; Target and Pathway Modulation, Galapagos NV, Mechelen, Belgium., Vandeghinste N; Kidney Therapeutic Area Group, Galapagos NV, Mechelen, Belgium, nick.vandeghinste@glpg.com., Christophe T; Therapeutic Area, Galapagos NV, Mechelen, Belgium, thierry.christophe@calliditas.com., Comas D; In Vivo Pharmacology, Galapagos SASU, Romainville, France, dcomas@novalix.com. |
| Source: | American journal of nephrology [Am J Nephrol] 2025; Vol. 56 (6), pp. 802-811. Date of Electronic Publication: 2025 Apr 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Karger Country of Publication: Switzerland NLM ID: 8109361 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9670 (Electronic) Linking ISSN: 02508095 NLM ISO Abbreviation: Am J Nephrol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1421-9670 |
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| DOI: | 10.1159/000545614 |
