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Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.

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Title: Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.
Authors: Su R; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wang H; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Li B; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wu R; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Xie Y; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Zi X; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Fan C; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Gao C; Brigham and Women's Hospital/Children's Hospital Boston, Joint Program in Transfusion Medicine, Harvard Medical School, Pathology Boston, Boston, USA., Li X; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wang C; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China. snwch@sina.com.
Source: Clinical rheumatology [Clin Rheumatol] 2025 Jun; Vol. 44 (6), pp. 2487-2500. Date of Electronic Publication: 2025 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949 (Electronic) Linking ISSN: 07703198 NLM ISO Abbreviation: Clin Rheumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.
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  Data: <searchLink fieldCode="AU" term="%22Su+R%22">Su R</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Wu+R%22">Wu R</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Zi+X%22">Zi X</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Fan+C%22">Fan C</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Gao+C%22">Gao C</searchLink>; Brigham and Women's Hospital/Children's Hospital Boston, Joint Program in Transfusion Medicine, Harvard Medical School, Pathology Boston, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China. snwch@sina.com.
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  Data: <searchLink fieldCode="JN" term="%228211469%22">Clinical rheumatology</searchLink> [Clin Rheumatol] 2025 Jun; Vol. 44 (6), pp. 2487-2500. <i>Date of Electronic Publication: </i>2025 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8211469 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1434-9949 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207703198%22">07703198 </searchLink><i>NLM ISO Abbreviation: </i>Clin Rheumatol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10067-025-07455-3
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        Text: English
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        StartPage: 2487
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      – TitleFull: Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.
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            – D: 01
              M: 06
              Text: 2025 Jun
              Type: published
              Y: 2025
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            – TitleFull: Clinical rheumatology
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