Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.

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Title: Low-dose IL-2 restores Tfh/Tfr imbalance and modulates B cell subset distribution in the pre-arthritis phase of the collagen-induced arthritis model.
Authors: Su R; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wang H; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Li B; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wu R; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Xie Y; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Zi X; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Fan C; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Gao C; Brigham and Women's Hospital/Children's Hospital Boston, Joint Program in Transfusion Medicine, Harvard Medical School, Pathology Boston, Boston, USA., Li X; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China., Wang C; Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Key Laboratory of Immunomicroecology, Taiyuan, Shanxi, China. snwch@sina.com.; Shanxi Province Engineering Research Center of Precision Medicine for Rheumatology, Shanxi, China. snwch@sina.com.
Source: Clinical rheumatology [Clin Rheumatol] 2025 Jun; Vol. 44 (6), pp. 2487-2500. Date of Electronic Publication: 2025 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949 (Electronic) Linking ISSN: 07703198 NLM ISO Abbreviation: Clin Rheumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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