Ontology accelerates few-shot learning capability of large language model: A study in extraction of drug efficacy in a rare pediatric epilepsy.

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Title: Ontology accelerates few-shot learning capability of large language model: A study in extraction of drug efficacy in a rare pediatric epilepsy.
Authors: Golnari P; Department of Population and Quantitative Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA., Prantzalos K; Department of Population and Quantitative Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA., Hood V; Dravet Syndrome Foundation, Inc, PO Box 3026, Cherry Hill, NJ 08034, USA., Meskis MA; Dravet Syndrome Foundation, Inc, PO Box 3026, Cherry Hill, NJ 08034, USA., Isom LL; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109-5632, USA., Wilcox K; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT 84112, USA., Parent JM; Department of Neurology and Michigan Neuroscience Institute, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Lal D; Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Center for Neurogenetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T., Cambridge, MA 02142, USA., Lhatoo SD; Department of Neurology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Goodkin HP; Department of Neurology and Pediatrics, University of Virginia, Charlottesville VA 22903, USA., Wirrell EC; Divisions of Child & Adolescent Neurology and Epilepsy, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA., Knupp KG; Department of Pediatrics and Neurology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Patel M; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus School of Medicine, Aurora, CO 80045, USA., Loeb JA; Department of Neurology and Rehabilitation, University of Illinois Chicago, Chicago, IL 60612, USA., Sullivan JE; Departments of Neurology and Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA., Harte-Hargrove L; CURE Epilepsy, Chicago, IL 60611, USA., Fureman BE; Epilepsy Foundation, 3540 Crain Highway, Suite 675, Bowie, MD 20716, USA., Buchhalter J; Department of Pediatrics, University of Calgary School of Medicine, Calgary AB T2N 4N1, Canada., Sahoo SS; Department of Population and Quantitative Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Source: International journal of medical informatics [Int J Med Inform] 2025 Sep; Vol. 201, pp. 105942. Date of Electronic Publication: 2025 Apr 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Science Ireland Ltd Country of Publication: Ireland NLM ID: 9711057 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8243 (Electronic) Linking ISSN: 13865056 NLM ISO Abbreviation: Int J Med Inform Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-8243
DOI:10.1016/j.ijmedinf.2025.105942