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Impact of L-arginine and liposomal vitamin C supplementation on quality of life and daily life activities in patients with COPD: a randomized, multicenter, single blind, placebo-controlled trial (ILDA study).

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Title: Impact of L-arginine and liposomal vitamin C supplementation on quality of life and daily life activities in patients with COPD: a randomized, multicenter, single blind, placebo-controlled trial (ILDA study).
Authors: Radovanovic D; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy; Coordinated Research Center on Respiratory Failure, University of Milan, Milano, Italy., Signorello JC; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy., Fuccia G; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy., Lazzaroni G; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy., Danzo F; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy., Guandalini GM; School of Medicine and Surgery, Università degli Studi di Milano, Milano, Italy., Massaro F; Cardiac and Pneumological Rehabilitation Medicine, Codogno Hospital, Lodi, Italy., Tursi F; Cardiac and Pneumological Rehabilitation Medicine, Codogno Hospital, Lodi, Italy., Santus P; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy; Coordinated Research Center on Respiratory Failure, University of Milan, Milano, Italy. Electronic address: pierachille.santus@unimi.it.
Source: European journal of internal medicine [Eur J Intern Med] 2025 Jun; Vol. 136, pp. 107-116. Date of Electronic Publication: 2025 May 01.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of L-arginine and liposomal vitamin C supplementation on quality of life and daily life activities in patients with COPD: a randomized, multicenter, single blind, placebo-controlled trial (ILDA study).
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  Data: <searchLink fieldCode="AU" term="%22Radovanovic+D%22">Radovanovic D</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy; Coordinated Research Center on Respiratory Failure, University of Milan, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Signorello+JC%22">Signorello JC</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Fuccia+G%22">Fuccia G</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Lazzaroni+G%22">Lazzaroni G</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Danzo+F%22">Danzo F</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Guandalini+GM%22">Guandalini GM</searchLink>; School of Medicine and Surgery, Università degli Studi di Milano, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Massaro+F%22">Massaro F</searchLink>; Cardiac and Pneumological Rehabilitation Medicine, Codogno Hospital, Lodi, Italy.<br /><searchLink fieldCode="AU" term="%22Tursi+F%22">Tursi F</searchLink>; Cardiac and Pneumological Rehabilitation Medicine, Codogno Hospital, Lodi, Italy.<br /><searchLink fieldCode="AU" term="%22Santus+P%22">Santus P</searchLink>; Department of Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milano, Italy; Coordinated Research Center on Respiratory Failure, University of Milan, Milano, Italy. Electronic address: pierachille.santus@unimi.it.
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  Data: <searchLink fieldCode="JN" term="%229003220%22">European journal of internal medicine</searchLink> [Eur J Intern Med] 2025 Jun; Vol. 136, pp. 107-116. <i>Date of Electronic Publication: </i>2025 May 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9003220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0828 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209536205%22">09536205 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Intern Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ejim.2025.04.039
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              Text: 2025 Jun
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